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Flavie STRAPPAZZON
Via Tazio Nuvolari 177 / 00141 Roma
36 years old, Two children
EDUCATION- PROFESSIONAL EXPERIENCE
01-2018-01-2020: Junior Principal Investigator “Roche per la Ricerca 2017”, Roche, 2 years, IRCCS Santa Lucia and Tor Vergata Univeristy, Rome, Italy “Preventing neurodegeneration in Multiple Sclerosis disease by activating mitophagy”
12-2014-11-2017: Junior Principal Investigator “Giovani Ricercatori”, Italian Ministry of Health . 3 years, IRCCS Santa Lucia, Rome, Italy. “Recovery of neuronal Parkinson’s disease neuronal functionality by modulation of Ambra1, a novel primer of mitophagy”
2015-2016 : Junior Principal Investigator “Trampoline grant”, French telethon, 1 year, IRCCS Santa Lucia, Rome, Italy.
“Recovery of a dystrophic phenotype by modulation of Ambra1, a novel primer of mitophagy”
2010- 2014 : Post-doctoral position in the laboratory directed by Prof. F. Cecconi, IRCCS Santa Lucia, Rome, Italy (Contracts from University of Rome) « Role of Ambra1 at the mitochondria”
2008-2010 : Post-doctoral training (Marie Curie fellow) in the laboratory directed by Prof. Mauro Piacentini « Study of the autophagic role of Transglutaminase 2 in vivo »
2004 - 2007 : PhD in Cellular Biology, Laboratory directed by Prof. Sadoul « Role of Alix and its partners Alg-2 and Pyk2 in neuronal death »
2004 : DEA of Cell Biology, Grenoble University, France « Study of the role of Alix in cell death induced by U.V»
2002 - 2003 : Master of Cell Biology and Physiology, Grenoble University, France.
1999 - 2001 : BSc of Cell Biology and Physiology, France
1999 High school diploma of Sciences, baccalaureate.
TECHNICAL SKILLS
Cellular Biology : Primary neuronal cultures, immunocytochemistry, immuno-
Histochemistry, Cell viability assays, transfection, FACS.
Confocal microscopy
Biochemistry: Western-Blot, Immunoprecipitation, kinase activity assays, Protein translation in vitro.
Molecular Biology : PCR, Cloning.
In vivo experiments: Perfusion of mice, collection of embryos/organs. Breeding mice
MEFs preparation- Genotype analysis.
INVITED PRESENTATIONS
• Oral presentation at the Gordon Research Conference « From the Basics in the Signaling and Molecular Aspect of Autophagy to the Identification of Therapeutic Targets” Ventura, CA, USA, March 2016
• Conference at the University of Rome, January 27th 2015, invited by Prof. F Cecconi.
• Oral presentation at the ECDO (European Cell Death Organization), entitled ‘Death pathways and beyond”, Geneva, Switzerland, October 2015
• Oral presentation at the Gordon Research Seminar on Autophagy in stress, development and disease, Italy, March 2014
• Oral presentation at the GRC (Gordon Research Conference) on Autophagy in stress, development and disease, Italy, March 2014
• Several Poster presentations at international meetings on Cell Death and Autophagy.
AWARDS
• Winner of a Marie Curie Scholarship to participate to the 14th Euroconference on Apoptosis, September 29-October-4, 2006 Sardegna, Italy
• Research Doctorate Fellowship, Ministère de la Recherche Française (2004-2007)
• Winner of a Keystone Scholarship to participate to the Keystone symposia on Cell Death, Vancouver, Canada, 24th-28th March, 2009.
• 2008-2010: Marie Curie Intra-European fellowship
• 2011-2012: Santa Lucia Foundation Fellowship
• 2014: Winner of a CFATG (Club Francophone de l’Autophagie) grant to participate to the Gordon Research Seminar (GRS) “Autophagy in stress, development and disease”, Lucca, Italy (15-16th March 2014)
• 2014: winner of the “Best talk” at the Gordon Research Seminar on Autophagy, 16th March, Italy
• 2017 : Price « Roche per la Ricerca 2017 » in Neurosciences